Parkinson's disease map
Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease in the world. Although many genetic and environmental factors contributing to the risk of PD have been identified, no unique causal mechanism is defined.
Information on various aspects of PD pathogenesis is rapidly increasing and needs to be efficiently organized, so that the resulting data is available for exploration and analysis. To that end, LCSB, in the collaboration with the Systems Biology Institute, Tokyo (SBI), has developed the Parkinson’s disease (PD) map (Fujita et al.).
The PD map is a manually curated knowledge repository established to describe molecular mechanisms of PD. It compiles literature-based information on PD into an easy to explore and freely accessible molecular interaction map and offers research-facilitating functionalities such as the overlay of experimental data and the identification of drug targets on the map (see user guide).
We envision the PD map as a hub for the PD community to deal with the exponentially increasing information on PD and we encourage the PD community to join forces and support this project by integrating their expertise to continuously refine and expand the knowledge within the PD map (see community).
With our continuous efforts in developing the computational tools and the joint curation of content with the PD community, we hope that thefreely accessible PD map opens new avenues in PD research.
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