Search
Startseite // Forschung // FSTM // DLSM // Research areas // Cancer Cell... // Publications
Imprimer

Publications

2022

Cipriani, C., Pires Pacheco, M. I., Kishk, A., Wachich, M., Abankwa, D., Schaffner-Reckinger, E., & Sauter, T. (2022). Bruceine D Identified as a Drug Candidate against Breast Cancer by a Novel Drug Selection Pipeline and Cell Viability Assay. Pharmaceuticals (Basel, Switzerland), 15(2).
Pavic, K., Chippalkatti, R., & Abankwa, D. (2022). Drug targeting opportunities en route to Ras nanoclusters. Advances in cancer research, 153, 63-99.
Top of Page

2021

Ahearn, I. M., Court, H. R., Siddiqui, F., Abankwa, D., & Philips, M. R. (2021, February 12). NRAS is unique among RAS proteins in requiring ICMT for trafficking to the plasma membrane. Life Science Alliance.
Chippalkatti, R., & Abankwa, D. (2021, February 05). Promotion of cancer cell stemness by Ras. Biochemical Society Transactions.
Glaab, E., Manoharan, G. B., & Abankwa, D. (2021). A Pharmacophore Model for SARS-CoV-2 3CLpro Small Molecule Inhibitors and in Vitro Experimental Validation of Computationally Screened Inhibitors. Journal of Chemical Information and Modeling, 61(8), 4082-4096.
Okutachi, S. O., Manoharan, G. B., Kiriazis, A., Laurini, C., Catillon, M., McCormick, F., Yli-Kauhaluoma, J., & Abankwa, D. (2021, February). A covalent calmodulin inhibitor as a tool to study cellular mechanisms of K-Ras-driven stemness. Frontiers in Cell and Developmental Biology.
Siddiqui, F. A., Vukic, V., Salminen, T. A., & Abankwa, D. (2021, June 04). Elaiophylin Is a Potent Hsp90/ Cdc37 Protein Interface Inhibitor with K-Ras Nanocluster Selectivity. Biomolecules.
Top of Page

2020

Abankwa, D., & Gorfe, A. A. (2020). Mechanisms of Ras Membrane Organization and Signaling: Ras Rocks Again. Biomolecules, 10(11).
Schommer, C., Sauter, T., Pang, J., & Abankwa, D. (2020). Proceedings of the AI4Health Lecture Series (2020). Paper presented at AI4Health Lectures Series (2020), Campus Belval, University of Luxembourg, Luxembourg.
Siddiqui, F. A., Alam, C., Rosenqvist, P., Ora, M., Sabt, A., Manoharan, G. B., Bindu, L., Okutachi, S. O., Catillon, M., Taylor, T., Abdelhafez, O. M., Lönnberg, H., Stephen, A. G., Papageorgiou, A. C., Virta, P., & Abankwa, D. (2020). PDE6D Inhibitors with a New Design Principle Selectively Block K‑Ras Activity. ACS Omega, 5(1), 832-842.
Yurugi, H., Zhuang, Y., Siddiqui, F. A., Liang, H., Rosigkeit, S., Zeng, Y., Abou-Hamdan, H., Bockamp, E., Zhou, Y., Abankwa, D., Zhao, W., Désaubry, L., & Rajalingam, K. (2020). A subset of flavaglines inhibits KRAS nanoclustering and activation. Journal of cell science, 133(12).
Top of Page

2019

Manoharan, G. B., Kopra, K., Eskonen, V., Harma, H., & Abankwa, D. (2019). High-throughput amenable fluorescence-assays to screen for calmodulin-inhibitors. Analytical Biochemistry, 572, 25-32.
Siddiqui, F. A., Parkkola, H., Manoharan, G. B., & Abankwa, D. (2019, October). Medium-Throughput Detection of Hsp90/Cdc37 Protein–Protein Interaction Inhibitors Using a Split Renilla Luciferase-Based Assay. SLAS Discovery.
Top of Page

2018

Buehler, U., Schulenburg, K., Yurugi, H., Solman, M., Abankwa, D., Ulges, A., Tenzer, S., Bopp, T., Thiede, B., Zipp, F., & Rajalingam, K. (2018). Targeting prohibitins at the cell surface prevents Th17-mediated autoimmunity. The EMBO journal, 37(16).
Vahter, J., Viht, K., Uri, A., Manoharan, G. B., & Enkvist, E. (2018). Thiazole- and selenazole-comprising high-affinity inhibitors possess bright microsecond-scale photoluminescence in complex with protein kinase CK2. Bioorganic & medicinal chemistry, 26(18), 5062-5068.
Top of Page

2017

Posada, I., Lectez, B., Sharma, M., Oetken-Lindholm, C., Yetukuri, L., Zhou, Y., Aittokallio, T., & Abankwa, D. (2017). rapalogs can promote cancer cell stemness in vitro in a Galectin-1 and H-ras-dependent manner. Oncotarget, Vol. 8((No. 27)), 44550-44566.
Posada, I., Lectez, B., Siddiqui, F., Oetken-Lindholm, C., Sharma, M., & Abankwa, D. (2017, August 21). Opposite feedback from mTORC1 to H-ras and K-ras4B downstream of SREBP1. Scientific Reports.
Sahlgren, C., Meinander, A., Zhang, H., Cheng, F., Preis, M., Xu, C., Salminen, T., Toivola, D., Abankwa, D., Rosling, A., Karaman, D., Salo-Ahen, O., Österbacka, R., Eriksson, J., Willför, S., Petre, I., Peltonen, J., Leino, R., Johnson, M., Rosenholm, J., & Sandler, N. (2017, September 11). Tailored Approaches in Drug Development and Diagnostics: From Molecular Design to Biological Model Systems. Advanced Healthcare Materials.
Top of Page

2016

Manoharan, G. B., Enkvist, E., & Uri, A. (2016). Combining chemical and genetic approaches for development of responsive FRET-based sensor systems for protein kinases. Biophysical Chemistry, 211, 39-48.
Top of Page

2015

Manoharan, G. B., Enkvist, E., Kasari, M., Viht, K., Zenn, M., Prinz, A., Filhol, O., Herbergb, F. W., & Uri, A. (2015). FRET-based screening assay using small-molecule photoluminescent probes in lysate of cells overexpressing RFP-fused protein kinases. Analytical Biochemistry.
Top of Page