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Christian Jäger

Christian Jäger

Postdoctoral researcher / Research associate

Fakultät oder Zentrum Luxembourg Centre for Systems Biomedicine
Forschungseinheit LCSB
Postadresse Université du Luxembourg
6, avenue du Swing
L-4367 Belvaux
Büroadresse BioTech II, 1.21
E-Mail
Telefon (+352) 46 66 44 6650

Metabolomics Platform Manager in the Enzymology & Metabolism group (Linster Lab)

Last updated on: Montag, den 05. Dezember 2016

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2019

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See detailMetabolite profiling of the cold adaptation of Pseudomonas putida KT2440 and cold‐sensitive mutants
Dethlefsen, Sarah; Jäger, Christian; Klockgether, Jens; Schomburg, Dietmar; Tümmler, Burkhard

in Environmental Microbiology Reports (2019)

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See detailIntegrative analysis of blood metabolomics and PET brain neuroimaging data for Parkinson's disease
Glaab, Enrico; Trezzi, Jean-Pierre; Greuel, Andrea; Jäger, Christian; Hodak, Zdenka; Drzezga, Alexander; Timmermann, Lars; Tittgemeyer, Marc; Diederich, Nico Jean; Eggers, Carsten

in Neurobiology of Disease (2019), 124(1), 555-562

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2018

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See detailCombining PET imaging and blood metabolomics data to improve machine learning models for Parkinson’s disease diagnosis
Glaab, Enrico; Trezzi, Jean-Pierre; Greuel; Jäger, Christian; Hodak, Zdenka; Timmermann, Lars; Tittgemeyer, Marc; Diederich, Nico Jean; Eggers, Carsten

Poster (2018, October 08)

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See detailIntegrated time-resolved multi-omics for understanding microbial niche ecology
Herold, Malte; Narayanasamy, Shaman; Martinez Arbas, Susana; Muller, Emilie; Kleine-Borgmann, Anna Luise; Lebrun, Laura; Roume, Hugo; Sheik, Abdul; Bessarab, Irina; Williams, Rohan; Gillece, John; Schupp, Jim; Keim, Paul; Jäger, Christian; Hoopmann, Michael; Li, Sujun; Tang, Haixu; Heintz, Anna; May, Patrick; Laczny, Cedric Christian; Wilmes, Paul

Poster (2018, August)

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See detailNatural variation of chronological aging in the Saccharomyces cerevisiae species reveals diet-dependent mechanisms of life span control
Jung, Paul; Zhang, Zhi; Paczia, Nicole; Jäger, Christian; Ignac, Tomasz; May, Patrick; Linster, Carole

in npj Aging and Mechanisms of Disease (2018), 4(3),

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See detailQuantification of Stable Isotope Traces Close to Natural Enrichment in Human Plasma Metabolites Using Gas Chromatography-Mass Spectrometry
Krämer, Lisa; Jäger, Christian; Trezzi, Jean-Pierre; Jacobs, Doris; Hiller, Karsten

in Metabolites (2018), 8(1), 15

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See detailItaconic acid indicates cellular but not systemic immune system activation
Meiser, Johannes; Kraemer, Lisa; Jäger, Christian; Madry, Henning; Link, Andreas; Lepper, Philipp M.; Hiller, Karsten; Schneider, Jochen

in Oncotarget (2018), 9(63),

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See detailCombining Metabolomics and Neuroimaging in mid-stage Parkinson’s Disease. A Proof of Concept for Cross-Fertilization.
Trezzi, Jean-Pierre; Greuel, Andrea; Glaab, Enrico; Hodak, Zdenka; Timmermann, Lars; Jäger, Christian; Diederich, Nico; Eggers, Carsten

in Neurology (2018), 90(15), 3066

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2017

See detailA study of the molecular mechanisms underlying teh response of human colorectal adenomacarcinoma enterocytes to prebiotics and probiotics
Greenhalgh, Kacy; Fritz, Joëlle; Letellier, Elisabeth; Ramiro Garcia, Javier; Halder, Rashi; Frachet Bour, Audrey; Baginska, Joanna; Ternes, Dominik; Jäger, Christian; Haan, Serge; Wilmes, Paul

Poster (2017)

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See detailErythritol is a pentose-phosphate pathway metabolite and associated with adiposity gain in young adults
Hootman, Katie C.; Trezzi, Jean-Pierre; Kraemer, Lisa; Burwell, Lindsay S.; Dong, Xiangyi; Guertin, Kristin A.; Jäger, Christian; Stover, Patrick J.; Hiller, Karsten; Cassano, Patricia A.

in Proceedings of the National Academy of Sciences of the United States of America (2017)

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See detailGlutathione Primes T Cell Metabolism for Inflammation
Mak, Tak W.; Grusdat, Melanie; Duncan, Gordon S.; Dostert, Catherine; Nonnenmacher, Yannic; Cox, Maureen; Binsfeld, Carole; Hao, Zhenyue; Brüstle, Anne; Itsumi, Momoe; Jäger, Christian; Chen, Ying; Pinkenburg, Olaf; Camara, Bärbel; Ollert, Markus; Bindslev-Jensen, Carsten; Vasiliou, Vasilis; Gorrini, Chiara; Lang, Philipp A.; Lohoff, Michael; Harris, Isaac S.; Hiller, Karsten; Brenner, Dirk

in Immunity (2017), 46(4), 675-689

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See detailDistinct metabolomic signature in cerebrospinal fluid in early parkinson's disease: Early Parkinson'S CSF Metabolic Signature
Trezzi, Jean-Pierre; Galozzi, Sara; Jäger, Christian; Barkovits, Katalin; Brockmann, Kathrin; Maetzler, Walter; Berg, Daniela; Marcus, Katrin; Betsou, Fay; Hiller, Karsten; Mollenhauer, Brit

in Movement Disorders (2017)

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See detailMetabolic profiling of body fluids and multivariate data analysis
Trezzi, Jean-Pierre; Jäger, Christian; Galozzi, Sara; Barkovits, Katalin; Marcus, Katrin; Mollenhauer, Brit; Hiller, Karsten

in MethodsX (2017), 4(1), 95-103

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2016

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See detailGene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages
Antony, Paul; Tallam, Aravind; Perumal, Thanneer Malai; Jäger, Christian; Fritz, Joëlle; Balling, Rudi; del Sol Mesa, Antonio; Michelucci, Alessandro; Vallar, Laurent

in PLoS ONE (2016)

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See detailA study of the molecular mechanisms underlying the response of human colorectal adenomacarcinoma enterocytes to prebiotics and probiotics
Greenhalgh, Kacy; Fritz, Joëlle; Letellier, Elisabeth; Frachet Bour, Audrey; Baginska, Joanna; Shah, Pranjul; Desai, Mahesh; Glaab, Enrico; Jäger, Christian; Haan, Serge; Wilmes, Paul

Poster (2016, June)

See detailMetabolic Profiling and Quantification of Neurotransmitters in Mouse Brain by Gas Chromatography-Mass Spectrometry: Metabolic Profiling of Neurotransmitters by GC-MS
Jäger, Christian; Hiller, Karsten; Buttini, Manuel

in Auwerx, Johan; Ackerman, Susan L.; Brown, Stephen D.; Justice, Monica J.; Nadeau, Joseph (Eds.) Current Protocols in Mouse Biology (2016)

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See detailDual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors
Lorendeau, Doriane; Rinaldi, Gianmarco; Boon, Ruben; Spincemaille, Pieter; Metzger, Kristine; Jäger, Christian; Christen, Stefan; Dong, Xiangyi; Kuenen, Sabine; Voordeckers, Karin; Verstreken, Patrik; Cassiman, David; Vermeersch, Pieter; Verfaillie, Catherine; Hiller, Karsten; Fendt, Sarah-Maria

in Metabolic Engineering (2016)

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See detailGeneration of genome-scale metabolic reconstructions for 773 members of the human gut microbiota
Magnusdottir, Stefania; Heinken, Almut Katrin; Kutt, Laura; Ravcheev, Dmitry; Bauer, Eugen; Noronha, Alberto; Greenhalgh, Kacy; Jäger, Christian; Baginska, Joanna; Wilmes, Paul; Fleming, Ronan MT; Thiele, Ines

in Nature Biotechnology (2016)

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See detailLoss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism
Meiser, Johannes; Delcambre, Sylvie; Wegner, André; Jäger, Christian; Ghelfi, Jenny; Fouquier d'Hérouël, Aymeric; Dong, Xiangyi; Weindl, Daniel; Stautner, Constantin; Nonnenmacher, Yannic; Michelucci, Alessandro; Popp, Oliver; Giesert, Florian; Schildknecht, Stefan; Kraemer, Lisa; Schneider, Jochen G.; Woitalla, Dirk; Wurst, Wolfgang; Skupin, Alexander; Vogt Weisenhorn, Daniela M.; Krüger, Rejko; Leist, Marcel; Hiller, Karsten

in Neurobiology of disease (2016), 89

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See detailA microfluidics-based in vitro model of the gastrointestinal human-microbe interface.
Shah, Pranjul; Fritz, Joëlle; Glaab, Enrico; Desai, Mahesh S.; Greenhalgh, Kacy; Frachet Bour, Audrey; Niegowska, Magdalena; Estes, Matthew; Jäger, Christian; Seguin-Devaux, Carole; Zenhausern, Frederic; Wilmes, Paul

in Nature communications (2016), 7

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See detailDistinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions
Zhang, Hui; Badur, Mehmet G.; Divakaruni, Ajit S.; Parker, Seth J.; Jäger, Christian; Hiller, Karsten; Murphy, Anne N.; Metallo, Christian M.

in Cell Reports (2016), 16(6), 1536--1547

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2015

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See detailThe neural stem cell fate determinant TRIM32 regulates complex behavioral traits
Hillje, Anna-Lena; Beckmann, Elisabeth; Pavlou, Maria Angeliki; Jäger, Christian; Pacheco, Maria; Sauter, Thomas; Schwamborn, Jens Christian; Lewejohann, Lars

in Frontiers in Cellular Neuroscience (2015)

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See detailThe Mouse Brain Metabolome: Region-Specific Signatures and Response to Excitotoxic Neuronal Injury
Jäger, Christian; Glaab, Enrico; Michelucci, Alessandro; Binz, Tina; Köglsberger, Sandra; Garcia, Pierre; Trezzi, Jean-Pierre; Ghelfi, Jenny; Balling, Rudi; Buttini, Manuel

in American Journal of Pathology (2015), 185(6), 1699-1712

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See detailIsotopologue ratio normalization for non-targeted metabolomics
Weindl, Daniel; Wegner, André; Jäger, Christian; Hiller, Karsten

in Journal of Chromatography. A (2015), 1389

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2014

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See detailFragment Formula Calculator (FFC): Determination of chemical formulas for fragment ions in mass spectrometric data
Wegner, André; Weindl, Daniel; Jäger, Christian; Sapcariu, Sean; Dong, Xiangyi; Stephanopoulos, Greg; Hiller, Karsten

in Analytical Chemistry (2014), 86(4), 22212228

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2012

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See detailThe metabolic response of P. putida KT2442 producing high levels of polyhydroxyalkanoate under single-and multiple-nutrient-limited growth: Highlights from a multi-level omics approach
Poblete-Castro, Ignacio; Escapa, Isabel F; Jäger, Christian; Puchalka, Jacek; Ming Chi Lam, Carolyn; Schomburg, Dietmar; Prieto, María Auxiliadora; Martins dos Santos, Vítor AP

in Microbial Cell Factories (2012)

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2009

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See detailMetaboliteDetector: comprehensive analysis tool for targeted and nontargeted GC/MS based metabolome analysis
Hiller, Karsten; Hangebrauk, Jasper; Jäger, Christian; Spura, Jana; Schreiber, Kerstin; Schomburg, Dietmar

in Analytical Chemistry (2009)

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