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Nicole Paczia

Nicole Paczia

Research Scientist

Fakultät oder Zentrum Luxembourg Centre for Systems Biomedicine
Forschungseinheit LCSB
Postadresse Université du Luxembourg
6, avenue du Swing
L-4367 Belvaux
Büroadresse BioTech II, 1.20
E-Mail
Telefon (+352) 46 66 44 5903
Fax (+352) 46 66 44 35903

Postdoc in the Enzymology & Metabolism group (Linster Lab)

Last updated on: Mittwoch, den 09. Juli 2014

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2019

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See detail3‑Phosphoglycerate Transhydrogenation Instead of Dehydrogenation Alleviates the Redox State Dependency of Yeast de Novo L‑Serine Synthesis
Paczia, Nicole; Becker, Julia; Conrotte, Jean-François; Cifuente, Javier O.; Guerin, Marcelo E.; Linster, Carole

in Biochemistry (2019)

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See detailNAD(P)HX dehydratase (NAXD) deficiency: a novel neurodegenerative disorder exacerbated by febrile illnesses
Van Bergen, Nicole; Guo, Yiran; Rankin, Julia; Paczia, Nicole; Becker-Kettern, Julia; Kremer, Laura; Pyle, Angela; Conrotte, Jean-François; Ellaway, Carolyn; Procopis, Peter; Prelog, Kristina; Homfray, Tessa; Baptista, Júlia; Baple, Emma; Wakeling, Matthew; Massey, Sean; Kay, Daniel; Shukla, Anju; Girisha, Katta; Lewis, Leslie; Santra, Saikat; Power, Rachel; Daubeney, Piers; Montoya, Julio; Ruiz-Pesini; Kovacs-Nagy, Reka; Pritsch, Martin; Ahting, Uwe; Thorburn, David; Prokisch, Holger; Taylor, Robert; Christodoulou, John; Linster, Carole; Ellard, Sian; Hakonarson, Hakon

in Brain: a Journal of Neurology (2019), 142(1), 50-58

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See detailFailure to eliminate a phosphorylated glucose analog leads to neutropenia in patients with G6PT and G6PC3 deficiency
Veiga-da-Cunha, Maria; Chevalier, Nathalie; Stephenne, Xavier; Defour, Jean-Philippe; Paczia, Nicole; Ferster, Alina; Achouri, Younes; Dewulf, Joseph P; Linster, Carole; Bommer, Guido T; Van Schaftingen, Emile

in Proceedings of the National Academy of Sciences of the United States of America (2019), 116(4), 1241-1250

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2018

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See detailNAD(P)HX repair deficiency causes central metabolic perturbations in yeast and human cells
Becker-Kettern, Julia; Paczia, Nicole; Conrotte, Jean-François; Zhu, Chenchen; Fiehn, Oliver; Jung, Paul; Steinmetz, Lars; Linster, Carole

in FEBS Journal (2018)

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See detailMillifluidic culture improves human midbrain organoid vitality and differentiation
Berger, Emanuel; Magliaro, Chiara; Paczia, Nicole; Monzel, Anna Sophia; Antony, Paul; Linster, Carole; Bolognin, Silvia; Ahluwalia, Arti; Schwamborn, Jens Christian

in Lab on a Chip - Miniaturisation for Chemistry and Biology (2018)

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See detailNatural variation of chronological aging in the Saccharomyces cerevisiae species reveals diet-dependent mechanisms of life span control
Jung, Paul; Zhang, Zhi; Paczia, Nicole; Jäger, Christian; Ignac, Tomasz; May, Patrick; Linster, Carole

in npj Aging and Mechanisms of Disease (2018), 4(3),

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2017

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See detailNit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione
Peracchi, Alessio; Veiga-da-Cunha, Maria; Kuhara, Tomiko; Ellens, Kenneth W; Paczia, Nicole; Stroobant, Vincent; Seliga, Agnieszka K; Marlaire, Simon; Jaisson, Stephane; Bommer, Guido T; Sun, Jin; Huebner, Kay; Linster, Carole; Cooper, Arthur J.L.; Van Schaftingen, Emile

in Proceedings of the National Academy of Sciences of the United States of America (2017), 1613736114

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2016

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See detailSaccharomyces cerevisiae Forms D-2-Hydroxyglutarate and Couples its Degradation to D-Lactate Formation via a Cytosolic Transhydrogenase.
Becker-Kettern, Julia; Paczia, Nicole; Conrotte, Jean-Francois; Kay, Daniel; Guignard, Cedric; Jung, Paul; Linster, Carole

in The Journal of Biological Chemistry (2016)

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