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Silvia Bolognin

Silvia Bolognin

Research scientist

Fakultät oder Zentrum Luxembourg Centre for Systems Biomedicine
Department Developmental and Cellular Biology
Postadresse Université du Luxembourg
6, avenue du Swing
L-4367 Belvaux
Büroadresse BioTech II, 3.20
E-Mail
Telefon (+352) 46 66 44 5905
Fax (+352) 46 66 44 5905

Postdoc in the Developmental & Cellular Biology group (Schwamborn Lab)

Last updated on: Mittwoch, den 09. Juli 2014

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2021

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See detailIntegrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening
Boussaad, Ibrahim; Cruciani, Gérald; Bolognin, Silvia; Antony, Paul; Dording, Claire; Kwon, Yong-Jun; Heuting, Peter; Fava, Eugenio; Schwamborn, Jens Christian; Krüger, Rejko

in Scientific Reports (2021)

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See detailMonitoring the neurotransmitter release of human midbrain organoids using a redox cycling microsensor as a novel tool for personalized Parkinson’s disease modeling and drug screening.
Zanetti, Cristian; Spitz, Sarah; Berger, Emanuel; Bolognin, Silvia; Smits, Lisa; Crepaz, Philipp; Rothbauer, Mario; Rosser, Julie M; Marchetti'Deschmann, Martina; Schwamborn, Jens Christian; Ertl, Peter

in Analyst (2021)

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2020

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See detailImpaired dopamine D3 and nicotinic acetylcholine receptor membrane localization in iPSCs-derived dopaminergic neurons from two Parkinson’s disease patients carrying the LRRK2 G2019S mutation
Bono, Federica; Mutti, Veronica; Devoto, Paola; Bolognin, Silvia; Schwamborn, Jens Christian; Missale, Cristina; Fiorentini, Chiara

in Neurobiology of Aging (2020)

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See detailA patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease.
Boussaad, Ibrahim; Obermaier, Carolin D.; Hanss, Zoé; Bobbili, Dheeraj R.; Bolognin, Silvia; Glaab, Enrico; Wołyńska, Katarzyna; Weisschuh, Nicole; De Conti, Laura; May, Caroline; Giesert, Florian; Grossmann, Dajana; Lambert, Annika; Kirchen, Susanne; Biryukov, Maria; Burbulla, Lena F.; Massart, Francois; Bohler, Jill; Cruciani, Gérald; Schmid, Benjamin; Kurz-Drexler, Annerose; May, Patrick; Duga, Stefano; Klein, Christine; Schwamborn, Jens Christian; Marcus, Katrin; Woitalla, Dirk; Vogt Weisenhorn, Daniela M.; Wurst, Wolfgang; Baralle, Marco; Krainc, Dimitri; Gasser, Thomas; Wissinger, Bernd; Krüger, Rejko

in Science translational medicine (2020), 12(560),

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See detailSynapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis
Gomez Giro, Gemma; Arias-Fuenzalida, Jonathan; Jarazo, Javier; Zeuschner, Dagmar; Ali, Muhammad; Possemis, Nina; Bolognin, Silvia; Halder, Rashi; Jäger, Christian; Kuper, Willemijn; van Hasselt, Peter; Zaehres, Holm; del Sol Mesa, Antonio; van der Putten, Herman; Schoeler, Hans; Schwamborn, Jens Christian

in Acta Neuropathologica Communications (2020)

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See detailReduced astrocytic reactivity in human brains and midbrain organoids with PRKN mutations
Kano, Masayoshi; Takanashi, Masashi; Oyama, Genko; Yoritaka, Asako; Hatano, Taku; Shiba-Fukushima, Kahori; Nagai, Makiko; Nishiyama, Kazutoshi; Hasegawa, Kazuko; Inoshita, Tsuyoshi; Ishikawa, Kei-ichi; Akamatsu, Wado; Imai, Yuzuru; Bolognin, Silvia; Schwamborn, Jens Christian; Hattori, Nobutaka

in NPJ Parkinson's Disease (2020)

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See detailPeptide-Imprinted Poly(hydroxymethyl 3,4-ethylenedioxythiophene) Nanotubes for Detection of Alpha Synuclein in Human Brain Organoids
Lee, Mei-Hwa; Liu, Kuan-Ting; Thomas, James Louis; Su, Zi-Lin; O'Hare, Danny; van Wüllen, Thea Maria; Modamio Chamarro, Jennifer; Bolognin, Silvia; Luo, Shyh-Chyang; Schwamborn, Jens Christian; Lin, Hung-Yin

in ACS Applied Nano Materials (2020)

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See detailEpitope imprinting of alpha-synuclein for sensing in Parkinson's brain organoid culture medium
Lee, Mei-Hwa; Thomas, James; Su, Zi-Lin; Yeh, Wen-Kuan; Monzel, Anna Sophia; Bolognin, Silvia; Schwamborn, Jens Christian; Yang, Chien-Hsin; Lin, Hung-Yin

in Biosensors and Bioelectronics (2020)

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See detailMachine learning-assisted neurotoxicity prediction in human midbrain organoids
Monzel, Anna Sophia; Hemmer, K; Smits, Lisa; Bolognin, Silvia; Lucarelli, P; Rosety, Isabel; Zagare, Alise; Antony, Paul; Nickels, SL; Krüger, Rejko; Schwamborn, Jens Christian

in Parkinsonism and Related Disorders (2020)

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See detailSingle-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids
Smits, Lisa; Magni, Stefano; Kinugawa, Kaoru; Grzyb, Kamil; Luginbühl, Joachim; Sabaté Soler, Sonia; Bolognin, Silvia; Shin, Jay; Mori, Eiichiro; Skupin, Alexander; Schwamborn, Jens Christian

in Cell and Tissue Research (2020)

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2019

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See detailImpaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients
Nickels, Sarah; Walter, Jonas; Bolognin, Silvia; Gerard, Deborah; Jäger, Christian; Qing, Xiaobing; Tisserand, Johan; Jarazo, Javier; Hemmer, Kathrin; Harms, Amy; Halder, Rashi; Lucarelli, Philippe; Berger, Emanuel; Antony, Paul; Glaab, Enrico; Hankemeier, Thomas; Klein, Christine; Sauter, Thomas; Sinkkonen, Lasse; Schwamborn, Jens Christian

in Parkinsonism and Related Disorders (2019)

See detailSingle-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids
Smits, Lisa; Magni, Stefano; Grzyb, Kamil; Antony, Paul; Krüger, Rejko; Skupin, Alexander; Bolognin, Silvia; Schwamborn, Jens Christian

E-print/Working paper (2019)

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See detailModeling Parkinson’s disease in midbrain-like organoids
Smits, Lisa; Reinhardt, Lydia; Reinhardt, Peter; Glatza, Michael; Monzel, Anna Sophia; Stanslowsky, Nancy; Rosato-Siri, Marcelo; Zanon, Alessandra; Antony, Paul; Bellmann, Jessica; Nicklas, Sarah; Hemmer, Kathrin; Qing, Xiaobing; Berger, Emanuel; Kalmbach, Norman; Ehrlich, Marc; Bolognin, Silvia; Hicks, Andrew; Wegner, Florian; Sterneckert, Jared; Schwamborn, Jens Christian

in NPJ Parkinson's Disease (2019)

See detailCultivation and characterization of human midbrain organoids in sensor integrated microfluidic chips
Spitz, Sarah; Zanetti, Cristian; Bolognin, Silvia; Muwanigwa, Mudiwa Nathasia; Smits, Lisa; Berger, Emanuel; Jordan, Christian; Harasek, Michael; Schwamborn, Jens Christian; Ertl, Peter

E-print/Working paper (2019)

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See detailNeural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality
Walter, Jonas; Bolognin, Silvia; Antony, Paul; Nickels, Sarah; Poovathhingal, Suresh; Salamanca, Luis; Magni, Stefano; Perfeito, Rita; Hoel, Fredrik; Qing, Xiaobing; Jarazo, Javier; Arias-Fuenzalida, Jonathan; Ignac, Tomasz; Monzel, Anna Sophia; Gonzalez-Cano, Laura; Pereira de Almeida, Luis; Skupin, Alexander; Tronstad, Karl; Schwamborn, Jens Christian

in Stem Cell Reports (2019)

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2018

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See detailMillifluidic culture improves human midbrain organoid vitality and differentiation
Berger, Emanuel; Magliaro, Chiara; Paczia, Nicole; Monzel, Anna Sophia; Antony, Paul; Linster, Carole; Bolognin, Silvia; Ahluwalia, Arti; Schwamborn, Jens Christian

in Lab on a Chip - Miniaturisation for Chemistry and Biology (2018)

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See detail3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing
Bolognin, Silvia; Fossépré, Marie; Qing, Xiaobing; Jarazo, Javier; Ščančar, Janez; Lucumi Moreno, Edinson; Nickels, Sarah; Wasner, Kobi; Ouzren, Nassima; Walter, Jonas; Grünewald, Anne; Glaab, Enrico; Salamanca, Luis; Fleming, Ronan M. T.; Antony, Paul; Schwamborn, Jens Christian

in Advanced Science (2018)

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See detailIn vivo Phenotyping of Human Parkinson’s Disease-Specific Stem Cells Carrying the LRRK2-G2019S Mutation Reveals Increased a-Synuclein Levels but Absence of Spreading
Hemmer, Kathrin; Smits, Lisa; Bolognin, Silvia; Schwamborn, Jens Christian

in Opera Medica et Physiologica (2018)

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2017

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See detailIn Vivo Phenotyping Of Parkinson-Specific Stem Cells Reveals Increased a-Synuclein Levels But No Spreading
Hemmer, Kathrin; Smits, Lisa; Bolognin, Silvia; Schwamborn, Jens Christian

in bioRxiv (2017)

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See detailDerivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells
Monzel, Anna Sophia; Smits, Lisa; Hemmer, Kathrin; Hachi, Siham; Lucumi Moreno, Edinson; Van Wüllen, Thea Maria; Jarazo, Javier; Walter, Jonas; Werthschulte, Inga; Boussaad, Ibrahim; Berger, Emanuel; Fleming, Ronan MT; Bolognin, Silvia; Schwamborn, Jens Christian

in Stem Cell Reports (2017)

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2015

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See detailRapid and robust generation of long-term self-renewing human neural stem cells with the ability to generate mature astroglia
Palm, Thomas; Bolognin, Silvia; Meiser, Johannes; Nickels, Sarah; Traeger, Claudia; Meilenbrock, Ralf-Leslie; Brockhaus, Johannes; Streitmueller, Miriam; Missler, Markus; Schwamborn, Jens Christian

in Scientific Reports (2015), 5

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