The rodent facility has been established to assist researchers in the development and analysis of various in vivo models including humanized and germ-free animals. The facility has the capacity to house more than 100 different mouse lines in 1500 IVC cages in the Breeding barrier under SOPF status. The Experimental barrier with a capacity for 600 mouse and 300 rat cages, is dedicated to studies on transgenic rodents and offers as well the possibility to realize BSL-2 activities and housing xenograft models. Genetically modified rodent lines can be generated by our Transgenic Core Unit and kept either as live animals or as cryopreserved sperm. The facility offers the possibility of running a broad number of experimental procedures on the premises, including stereotaxic surgical procedures and motor behavior equipment as the Catwalk. Additionally, humanized mouse models can be provided within an SPF environment. The Germ-free Unit is established within the Breeding barrier to ensure a controlled health status. For colonization studies, germ-free mice can be inoculated with a suspension of a specific microbe (mono-colonization), a defined finite group of microbes, or a polymicrobial mixture. This unit also employs a Sealed Positive Pressure IVC system to achieve the type of germ-controlled environment.

For any questions, do not hesitate to contact the mouse facility via email.